American, United lost combined $1.6 billion to end 2021 amid Omicron COVID-19 surge Posted on January 20, 2022 by Travel editor American and United, two of the three largest airlines in the world, posted combined losses of more than $1.5 billion in the last quarter of 2021 — indicating that COVID-19 still is hindering global air travel. Post navigation Crestron Road Trip Europe coming to 19 countriesAnother European holiday hotspot lifts travel restrictions for Brits