Much of Europe remains at the CDC’s highest travel risk as other regions improve Posted on April 12, 2022 by Travel editor The CDC designates a destination a Level 4 risk when more than 500 cases per 100,000 residents have been registered in the past 28 days. Post navigation Letter to Dr. Ashish Jha on Pandemic Travel RestrictionsAirline industry urges end to mask requirements as deadline approaches: “We need to remove these mandates”